GLP-1 Patient Recruitment: A Scalable Strategy for Multi-Study Success

As the clinical landscape for GLP-1 therapies continues to expand, so does the pressure on sponsors to meet enrollment goals. Recruiting qualified patients for GLP-1 trials has become a critical bottleneck — and for sponsors managing multi-study GLP-1 programs, the challenge is even greater.

In this blog, we explore how Trialbee’s technology-powered platform offers a GLP-1 patient recruitment strategy that scales, even in the face of complex eligibility criteria, intense competition, and shifting regulatory demands.

Why GLP-1 Patient Recruitment Is More Challenging Than Ever

Trials designed to evaluate the safety and efficacy of GLP-1 receptor agonists hold great promise for patients with chronic diseases. However, enrolling eligible participants is increasingly difficult due to several converging factors:

  1. Increased Competition and Market Noise – The clinical trial ecosystem is saturated with concurrent GLP-1 trials, all competing for overlapping patient populations. With multiple sponsors targeting the same recruitment pools, cutting through the noise is essential.
  2. Shrinking Pool of GLP-1 Naïve Patients – Many GLP-1 clinical trials require patients who have not received GLP-1 treatment recently — often within a 3-month window. However, the mainstream adoption of GLP-1 therapies means that treatment-naïve participants are increasingly hard to find.
  3. Complex Protocols and Tight Eligibility Criteria – Strict requirements around BMI, HbA1c thresholds, and comorbid conditions further limit the available patient population. These complex inclusion and exclusion criteria elevate the burden on trial sites.
  4. Ineffective, Outdated Recruitment Tactics – Traditional site-based recruitment strategies alone cannot address the scale and diversity required for multi-study GLP-1 program enrollment. Engaging underrepresented populations demands new channels and personalized outreach.

Redefining GLP-1 Patient Recruitment at the Program Level

At Trialbee, we’re reshaping how recruitment is managed for GLP-1 clinical trial programs — empowering sponsors with a centralized, data-driven approach that delivers scalability, control, and visibility.

✔ Real-Time Program Visibility with Honey™

Our proprietary Honey Platform™ gives sponsors a macro and micro view of recruitment progress across their entire GLP-1 program — all in real time. From analytics dashboards to recruitment funnel performance, Honey centralizes insights in one unified location.

✔ Smart Patient Routing Across Multi-Study Programs

Honey’s intelligent routing algorithm matches patients with the most appropriate trial or cohort within your multi-study GLP-1 program, improving the likelihood of enrollment success.

✔ Licensed Secondary Screening

With complex GLP-1 eligibility criteria, our live secondary screening process — conducted by licensed medical professionals — ensures precise patient qualification, easing the operational burden on trial sites and improving enrollment efficiency.

✔ Seamless Re-Matching for Greater Yield

Patients who were previously disqualified from one study can be re-matched to another suitable trial within your program using Honey’s built-in logic. This recycling of potential participants helps maximize your recruitment investments.

✔ Sponsor-Specific GLP-1 Patient Registry

Trialbee maintains a sponsor-specific registry of interested and pre-screened patients. This continuously engaged pool can be reactivated and directed toward new trials or cohorts as they launch within your GLP-1 program.

A Modern, Scalable GLP-1 Recruitment Strategy

By leveraging Honey and the expertise of Trialbee’s global team, sponsors can confidently scale their GLP-1 patient recruitment strategy — across trials, countries, and cohorts. With support in over 60 countries and experience managing programs with 700+ sites in 20+ countries, Trialbee is a trusted partner to top global pharmaceutical sponsors.

Nearly one-third of our work involves multi-study program recruitment — including some of the largest and most complex GLP-1 trials in the world.

Take Control of Your GLP-1 Program Recruitment

The landscape is competitive, the timelines are tight, and the stakes are high — but your recruitment strategy doesn’t have to feel overwhelming. With Trialbee, you gain a GLP-1 recruitment strategy that’s built to scale with your program’s complexity.

Are you ready to transform your GLP-1 recruitment?
Let’s talk about how Trialbee can help you simplify, scale, and succeed.